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One aspect of this study that may be missed are the overall excellent responses achieved with only a moderate dose of methotrexate, highlighting the potency of methotrexate as a dmard which can often be overlooked in clinical trials that typically enroll only subjects with inadequate responses to methotrexate.
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some parents report that they asked for or were given the option to do the entire methotrexate iv treatment or at least the hydration part at home, with the child wearing a backpack for the iv containers.